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| 003 | MX-MdCICY | ||
| 005 | 20250625140632.0 | ||
| 040 | _cCICY | ||
| 090 | _aB-10480 | ||
| 245 | 1 | 0 | _aProteomics and regulomics: the yin and yang of functional genomics |
| 490 | 0 | _vMass Spectrometry Reviews, 23(1), p.25-33, 2003 | |
| 520 | 3 | _aProtein analysis is a field of research with a long history. Recently, the development of a series of proteomics approaches, i.e., simultaneous analyses on all or a majority of proteins in a cell at a given state, has reinvigorated protein analyses. Mass Spectrometry also developed into one of the most versatile technical tools supporting or even enabling many proteomicsoriented approaches, providing a convenient link between experimental protein analysis and the corresponding amino acid sequences. Thus direct links to the genomic sequence can be established, which opens the door for a synergistic combination with genomic sequence analysis. This review focuses especially on aspects of genome-wide transcription control, regulomics in analogy to all the other -omics, and how a combination of MS-based proteomics with in silico regulomics analyses can produce synergistic effects in the quest to understand how cells function. This is illustrated on a real life example showing how the MS-analysis and in silico promoter analysis can extend the list of candidates for signaling pathways, here the MAP kinase pathway | |
| 650 | 1 | 4 | _aPROTEOMICS |
| 650 | 1 | 4 | _aREGULAMICS |
| 650 | 1 | 4 | _aFUNCTIONAL GENOMICS |
| 700 | 1 | 2 | _aWerner, T. |
| 856 | 4 | 0 |
_uhttps://drive.google.com/file/d/1UIy-N3WgyQDFZOoof5qtTQdgyDENjhlQ/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
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