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245 1 0 _aFormation of self-organized nanoparticles by lecithin/chitosan ionic interaction
490 0 _vPharmaceutical Nanotechnology, 324(1), p.67-73, 2006
520 3 _aIn this work the production of auto-assembled nanoparticles obtained by the mixing of chitosan and lecithin is presented. The size and surface charge of the nanoparticles were studied as function of the weight ratio between components, the viscosity of the polysaccharide and the pH of the colloidal suspension. In order to elucidate the structure of nanoparticles, micro-FT-IR and elastic neutron scattering experiments have been performed. Results evidenced a strong electrostatic interaction between components and a structure that is neither that of homogeneous spheres nor of coated unilamellar vesicles. Preliminary encapsulation experiments with progesterone, as model lipophilic drug, showed good encapsulation efficiencies.
650 1 4 _aCHITOSAN
650 1 4 _aLECITHIN
650 1 4 _aSELF-ORGANIZING STRUCTURES
650 1 4 _aNANOPARTICLES
700 1 2 _aSonvico, F.
700 1 2 _aCagnani, A.
700 1 2 _aRossi, A.
700 1 2 _aMotta, S.
700 1 2 _aDi Bari, M.T.
700 1 2 _aCavatorta, F.
700 1 2 _aAlonso, M.J.
700 1 2 _aAlonso, M.J.
700 1 2 _aColombo, A.
856 4 0 _uhttps://drive.google.com/file/d/1v3ICmaROVo0pyAdBAo212PwefB59MuT0/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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