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245 1 0 _aThe use of the nonradioactive digoxigenin chemiluminescent technology for plant genomic Southern blot hybridization: a comparison with radioactivity
490 0 _vTransgenic Research, 2(2), p.115-120, 1993
520 3 _aA nonradioactive labelling and detection method for plant genomic DNA analysis is compared to the radioactive method. The radioisotopes are replaced by a nucleotide, digoxigenin-11-dUTP, and the signal detection is accomplished by the enzymatic reaction of alkaline phosphatase, conjugated to anti-digoxigenin antibodies, with the chemiluminescent substrate AMPPD 3-(2'-spiroadamantane)-4-methoxy-4(3"phosphorytoxy)phenyl-1, 2-dioxetane). The sensitivity of the radioactive and nonradioactive methods are directly compared using identical Southern blots subjected to the radioactive and nonradioactive detection. The advantages of this nonradioactive method are discussed.
650 1 4 _aCHEMILUMINESCENCE
650 1 4 _aDIGOXIGENIN
650 1 4 _aNONRADIOACTIVE
650 1 4 _aPLANT DNA
650 1 4 _aSOUTHERN BLOT HYBRIDIZATION
700 1 2 _aNeuhaus-Url, G.
700 1 2 _aNeuhaus, G.
856 4 0 _uhttps://drive.google.com/file/d/17vGVLjlNja-QFc3bes7AbbFjy6UJzg6y/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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