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245	1	0	_aPhysicochemical Characterization and Antioxidant Activity of Quercetin-Loaded Chitosan Nanoparticles
490	0		_vJournal of Applied Polymer Science, 107(2), p.891-897, 2008
520	3		_aQuercetin is an abundant flavonoid in food plants with numerous biological activities and widely used as a potent antioxidant. Being sparingly soluble in water and subject to degradation in aqueous intestinal fluids, the absorption of quercetin is limited upon oral administration. In the present study, chitosan nanoparticles and quercetin-loaded nanoparticles were prepared based on the ionic gelation of chitosan with tripolyphosphate anions. The encapsulation of quercetin in the chitosan nanoparticles were confirmed by differential scanning calorimetry, X-ray powder diffractometry, Fourier transformed infrared spectroscopy, ultraviolet-visible spectrum, and fluorescence spectrum. The morphology of the nanoparticles was characterized by atomic force microscopy. The antioxidant activity of the quercetin-nanoparticles was also evaluated in vitro by two different methods (free radical scavenging activity test and reducing power test), which indicates that inclusion of quercetin in chitosan nanopaticles may be useful in improving the bioavailabilty of quercetin.
650	1	4	_aQUERCETIN
650	1	4	_aCHITOSAN
650	1	4	_aNANOPARTICLES
650	1	4	_aCHARACTERIZATION
650	1	4	_aANTIOXIDANT
700	1	2	_aZhang, Y.
700	1	2	_aYang, Y.
700	1	2	_aTang, K.
700	1	2	_aHu, X.
700	1	2	_aZou, G.
856	4	0	_uhttps://drive.google.com/file/d/1qY2LDwxUFprIgSCOtsAgJiCGPWfhYv91/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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