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| 003 | MX-MdCICY | ||
| 005 | 20250625140647.0 | ||
| 040 | _cCICY | ||
| 090 | _aB-11254 | ||
| 245 | 1 | 0 | _aElastase-induced hvdrolvsis of synthetic solid subsrates: poly(ester-urea-urethane)and poly(ether-urea-urethane) |
| 490 | 0 | _vBioMaterials, 17, p.2381-2388, 1996 | |
| 520 | 3 | _aHuman neutrophil elastase (HNE)and porcine pancreatic elastase (PPE)were incubated with two radiolabelled model poly(urethane)s, a poly(ester-urea-urethane)containing ['4C]toluene diisocyanate ([14C]TDl), poly(caprolactone)(PCL)and ethylenediamine (ED), and a poly(ether-urea-urethane)containing [14C]TDI, poly(tetramethylene oxide)(PTMO)and ED. Ten-fold more radioactive carbon was released when PPE was incubated with ['4C]TDI/PCLIED than when HNE was used. The PPE-induced radioactive carbon release was significantly reduced by a specific elastase inhibitor. Ten-fold less radioactive carbon was released when ['4C]TDI/PTMOIED was incubated with PPE as compared to ['4C]TDI/PCL/ED. Since neutrophils, which contain elastolytic activity, are present during the inflammatory response, the stability of biomaterials used in implanted devices may be affected. | |
| 650 | 1 | 4 | _aPOLY(URETHANE)S |
| 650 | 1 | 4 | _aBIODEGRADATION |
| 650 | 1 | 4 | _aNEUTROPHIL |
| 650 | 1 | 4 | _aINFLAMMATORY RESPONSE |
| 650 | 1 | 4 | _aHUMAN ELASTASE |
| 650 | 1 | 4 | _aPORCINE ELASTASE |
| 700 | 1 | 2 | _aLabow, R.S. |
| 700 | 1 | 2 | _aErfle, D.J. |
| 700 | 1 | 2 | _aSanterre, J.P. |
| 856 | 4 | 0 |
_uhttps://drive.google.com/file/d/1o8jRcW3UzhmfJzFsnUfpLJvBfA7arjas/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
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