000 02688nam a2200277Ia 4500
003 MX-MdCICY
005 20250625140647.0
040 _cCICY
090 _aB-11293
245 1 0 _aA General Description of Detachment for Multidimensional Modelling of Biofilms
490 0 _vBiotechnology and BioEngineering, 91(6), p.651-669, 2007
520 3 _aA general method for describing biomass detachment in multidimensional biofilm modelling is introduced. Biomass losses from processes acting on the entire surface of the biofilm, such as erosion, are modelled using a continuous detachment speed function Fdet. Discrete detachment events, i.e. sloughing, are implicitly derived from simulations. The method is flexible to allow Fdet to take several forms, including expressions dependent on any state variables such as the local biofilm density. This methodology for biomass detachment was integrated with multidimensional (2D and 3D)particlebased multispecies biofilm models by using a novel application of the level set method. Application of the method is illustrated by trends in the dynamics of biofilms structure and activity derived from simulations performed on a simple model considering uniform biomass (case study I)and a model discriminating biomass composition in heterotrophic active mass, extracellular polymeric substances (EPS)and inert mass (case study II). esults from case study I demonstrate the effect of applied detachment forces as a fundamental factor influencing steady-state biofilm activity and structure. Trends from experimental observations reported in iterature were correctly described. For example, simulation results indicated that biomass sloughing is reduced whenerosion forces are increased. Case study II illustrates the application of the detachment methodology to systems with non-uniform biomass composition. Simulations carried out at different bulk concentrations of substrate show changes in biofilm structure (in terms of shape, density and spatial distribution of biomass components)and activity (in terms of oxygen and substrate consumption)as a consequence of either oxygen-limited or substrate-limited growth.
650 1 4 _aBIOFILM
650 1 4 _aDETACHMENT
650 1 4 _aEROSION
650 1 4 _aSLOUGHING
650 1 4 _aINDIVIDUAL-BASED MODELLING
650 1 4 _aEPS
650 1 4 _aLEVEL SET
700 1 2 _aJoao De Bivar Xavier
700 1 2 _aPicioreanu, C.
700 1 2 _aVan Loosdrecht, M.C.M.
856 4 0 _uhttps://drive.google.com/file/d/1rW_wJyqjf6BtfTS69kUyi0TdKrCZ4reU/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942 _2Loc
_cREF1
008 250602s9999 xx |||||s2 |||| ||und|d
999 _c45518
_d45518