| 000 | 02275nam a2200301Ia 4500 | ||
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| 003 | MX-MdCICY | ||
| 005 | 20250625140653.0 | ||
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| 090 | _aB-11593 | ||
| 245 | 1 | 0 | _aSynthesis of a Molecularly Imprinted Polymer for the Solid-phase Extraction of Betulin and Betulinic Acid from Plane Bark |
| 490 | 0 | _vPhytoChemical Analysis, 21(2), p.180-185, 2010 | |
| 520 | 3 | _aPlant extracts are usually complex mixtures of various polarity compounds and their study often includes a purifi cation step, such as solid-phase extraction (SPE), to isolate interest compounds prior analytical investigations. Molecularly imprinted polymers (MIPs)are a new promising type of SPE material which off er tailor-made selectivity for the extraction of trace active components in complex matrices. Numerous specifi c cavities that are sterically and chemically complementary of the target molecules, are formed in imprinted polymers. A molecularly imprinted polymer (MIP)was synthesised in order to trap a specifi c class of triterpene, including betulin and betulinic acid from a methanolic extract of plane bark. Methodology - Imprinted polymers were synthesised by thermal polymerisation of betulin as template, methacrylic acid (MAA)or acrylamide (AA)as functional monomer, ethylene glycol dimethacrylate as crosslinking agent and chloroform as porogen. Afterwards, MAA- and AA-MIPs were compared with their non-imprinted polymers (NIPs)in order to assess the selectivity vs betulin and its derivatives. Recovered triterpenes were analysed by HPLC during MIP-SPE protocol. Results - After SPE optimisation, the MAA-imprinted polymer exhibited highest selectivity and recovery (better than 70 | |
| 650 | 1 | 4 | _aMOLECULARLY IMPRINTED POLYMER |
| 650 | 1 | 4 | _aMIP |
| 650 | 1 | 4 | _aSOLID-PHASE EXTRACTION |
| 650 | 1 | 4 | _aSPE |
| 650 | 1 | 4 | _aBETULIN |
| 650 | 1 | 4 | _aBETULINIC ACID |
| 650 | 1 | 4 | _aTRITERPENE |
| 650 | 1 | 4 | _aPLANE BARK EXTRACT |
| 700 | 1 | 2 | _aClaude, B. |
| 700 | 1 | 2 | _aViron-Lamy, C. |
| 700 | 1 | 2 | _aHaupt, K. |
| 700 | 1 | 2 | _aMorin, P. |
| 856 | 4 | 0 |
_uhttps://drive.google.com/file/d/1KY-I4CuFUF3r1iRzwDr1k9SIj7GbqTlB/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
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