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090			_aB-11736
245	1	0	_aMegaplasmids of Aerobic Hydrogenotrophic and Carboxidotrophic Bacteria
490	0		_vMicrobiol Monographs, 11, p. 239-270, 2009
520	3		_aThe hydrogen-oxidizing bacterium Ralstonia eutropha H16 and the carbon monoxide-oxidizing bacterium Oligotropha carboxidovorans OM5 carry key genetic determinants for their respective forms of lithoautotrophic metabolism on megaplasmids. In R. eutropha H16 genetic information for the H 2 -oxidizing system and for CO 2 fixation via the Calvin-Benson-Bassham cycle is located on the 452-kb megaplasmid pHG1. In addition, pHG1 harbors clusters of genes for denitrification and for degradation of aromatic compounds. The 133-kb megaplasmid pHCG3 is the genetic basis for CO oxidation in O. carboxidovorans OM5. Aside from the aerobic CO dehydrogenase, pHCG3 also encodes Calvin cycle enzymes and a dimeric hydrogenase. In both cases there is an interdigitation of megaplasmidbased and chromosomally encoded functions, indicating that these megaplasmids are, although not strictly essential for viability, an integral part of the genome.
700	1	2	_aSchwartz, E.
856	4	0	_uhttps://drive.google.com/file/d/199HHxLy1d5tHsb9KMpHEn5GGW-cIx86K/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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