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245 1 0 _aAliphaticp olyestersI I. The degradation of poly (DL-lace), poly (E-caprolactone), and their copolymersin viva
490 0 _v8ioMaterials, 2, p.215-220, 1981
520 3 _aThe mechanisms of biodegradation of poly( 01 qactide), poly(ecaprolactone), and copolymers of Ecaprolactone with DL -dilactide, s-valerolactone, and DL -c-decalactone in rabbit were shown to be qualitatively similar. However, the rate of the first stage of the degradation process, nonenzymatic random hydrolytic chain scission, varied by an order of magnitude and was dependent on morphological as well as chemical effects. Weight loss was generally not observed until the molecular weight had decreased to 15 000 or less. Poly( DL -lactide)differed from the other polyesters studied, the rate of chain scission increasing after the commencement of weight loss. The rate of weight loss was greater and the period prior to weight loss was shorter when the comonomer content of copolymers of feaprolactone was sufficient to reduce the melting point of Ecaproate sequences to body temperature.
700 1 2 _aPitt, C.G.
700 1 2 _aGratzel, M.M.
700 1 2 _aKimmel, G.L.
700 1 2 _aSurles, J.
700 1 2 _aSchindler, A.
856 4 0 _uhttps://drive.google.com/file/d/1Kh68NMPHeflVcfolXIRwlONXTqCyxArg/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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