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090 _aB-12946
245 1 0 _aNanoparticle Formulation for Controlled Release of Capsaicin
490 0 _vJournal of NanoScience and Nanotechnology, 11(5), p.4586-4591, 2011
520 3 _aCapsaicin might be an effective pharmacological agent for the treatment of discogenic back pain due to its effect on pain control neuronal degeneration. Therefore, capsaicin-loaded nano- and micro-particles for sustained release were formulated by nano-precipitation or oil-in-water single emulsion solvent evaporation/extraction method. First, the capsaicin-loaded PLGA nanoparticles were prepared by nano-precipitation method. By increasing the volume of oil-water ratio from 1:2 to 1:5, slight changes in size from 162±3 nm to 153±3 nm and in drug loading efficiency from 25
650 1 4 _aCAPSAICIN
650 1 4 _aCONTROLLED RELEASE
650 1 4 _aPLLA
650 1 4 _aNANOPARTICLE
700 1 2 _aKim, S.
700 1 2 _aKim, J.C.
700 1 2 _aSul, D.
700 1 2 _aHwang, S.W.
700 1 2 _aLee, S.H.
700 1 2 _aKim, Y.H.
700 1 2 _aTae, G.
856 4 0 _uhttps://drive.google.com/file/d/1ZzB4wisNF2L6pDtxN7xl7AqldBaxoWle/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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