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| 003 | MX-MdCICY | ||
| 005 | 20250625153920.0 | ||
| 040 | _cCICY | ||
| 090 | _aB-13334 | ||
| 245 | 1 | 0 | _aRibosome biogenesis: of knobs and RNA processing |
| 490 | 0 | _vExperimental Cell Research, 296(1), p.43-50, 2004 | |
| 520 | 3 | _aThe synthesis of ribosomes in eukaryotes involves processing of pre-ribosomal RNA (pre-rRNA)and sequential assembly of a large number of ribosomal proteins on the rRNAs. Although we have gained tremendous insights into the processing of pre-rRNA intermediates in the last three decades, little was known about the dynamic nature of ribosome biogenesis. Only recently the development of efficient affinitypurification procedures and mass-spectrometry techniques has allowed the isolation of large pre-ribosomal complexes, which led to the identification of several ribosome assembly intermediates and a large number of novel ribosome assembly factors. In this mini-review, we summarize some of the discoveries that have been made in the field of ribosome biogenesis in the past 30 years and highlight some key aspects about what remains to be learned. | |
| 650 | 1 | 4 | _aSSU PROCESSOME |
| 650 | 1 | 4 | _a90S PRE-RIBOSOME |
| 650 | 1 | 4 | _aPRE-RRNA PROCESSING |
| 650 | 1 | 4 | _aU3 SNORNA |
| 650 | 1 | 4 | _aTAP AFFINITY PURIFICATION |
| 650 | 1 | 4 | _aPROTEOMICS |
| 700 | 1 | 2 | _aGranneman, S. |
| 700 | 1 | 2 | _aBaserga, S.J. |
| 856 | 4 | 0 |
_uhttps://drive.google.com/file/d/1YLhTlxOPj9MdlOKpedFJQt-MY8reHg8D/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
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