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245 1 0 _aCodon-Anticodon Assignment and Detection of Codon Usage Trends in Seven Microbial Genomes
490 0 _vMicrobial & Comparative Genomics, 2(4), p.299-312, 1997
520 3 _aWe have assigned codon-anticodon recognition patterns for the whole set of transfer RNAs of Haemophilus influenzae Rd, Methanococcus jannaschii, and Synechocystis sp. PCC6803 using sequence information derived from the complete genome sequence of these organisms and have tabulated them along with those previously reported for Escherichia coli, My¬ coplasma genitalium, Mycoplasma pneumoniae, and Saccharomyces cerevisiae. Using the re¬ sulting codon-anticodon tables, the bias in codon usage of genes encoding the entire protein and ribosomal protein complement of each of the seven microbial genomes was analyzed.Then, the codon adaptation index (CAIrp)for each protein gene was calculated using the codon usage preference of the ribosomal protein genes of the corresponding organism. Of the seven genomes examined, six showed CAIrp scores that roughly coincided with the ex¬ pected level of gene expression. The result demonstrates that CAIrp analysis may be useful for prediction of the expression level of unknown genes when all or at least considerable portions of the genome sequence are available.
700 1 2 _aNakamura, Y.
700 1 2 _aTabata, S.
856 4 0 _uhttps://drive.google.com/file/d/1CEWzZTjKKJzfU3xY1B5Gqi_l1QOkbsnz/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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