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090			_aB-13810
245	1	0	_aBrassinosteroids inhibit pathogen-associated molecular pattern-triggered immune signaling independent of the receptor kinase BAK1
490	0		_vPNAS, 109(1), p.303-308, 2012
520	3		_aPlants and animals use innate immunity as a first defense against pathogens, a costly yet necessary tradeoff between growth and immunity. In Arabidopsis, the regulatory leucine-rich repeat receptor- like kinase (LRR-RLK)BAK1 combines with the LRR-RLKs FLS2 and EFR in pathogen-associated molecular pattern (PAMP)-triggered mmunity (PTI)and the LRR-RLK BRI1 in brassinosteroid (BR)- mediated growth. Therefore, a potential tradeoff between these pathways mediated by BAK1 is often postulated. Here, we show a unidirectional inhibition of FLS2-mediated immune signaling by BR perception. Unexpectedly, this effect occurred downstream or ndependently of complex formation with BAK1 and associated downstream phosphorylation. Thus, BAK1 is not rate-limiting in these pathways. BRs also inhibited signaling triggered by the BAK1-independent recognition of the fungal PAMP chitin. Our results suggest a general mechanism operative in plants in which BR-mediated growth directly antagonizes innate immune signaling
650	1	4	_aFLAGELLIN SENSING
650	1	4	_aBRASSINOSTEROID INSENSITIVE
650	1	4	_aBRI
650	1	4	_aASSOCIATED KINASE
650	1	4	_aCROSS-TALK
700	1	2	_aAlbrecht, C.
700	1	2	_aBoutrot, F.
700	1	2	_aSegonzac, C.
700	1	2	_aSchwessinger, B.
700	1	2	_aGimenez-Ibanez, S.
700	1	2	_aChinchilla, D.
700	1	2	_aRathjen, J.P.
700	1	2	_aRathjen, J.P.
700	1	2	_aZipfel, C.
856	4	0	_uhttps://drive.google.com/file/d/1DOOX2aI1Ygb72TdKOnkPsEOVJhH_BhF2/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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