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090 _aB-14691
245 1 0 _aTwo-Dimensional SDS-PAGE Fractionation of Biological Samples for Biomarker Discovery
490 0 _vProteomics for Biomarker Discovery, p.151-165, 2013
520 3 _aTwo-dimensional electrophoresis is still a very valuable tool in proteomics, due to its reproducibility and its ability to analyze complete proteins. However, due to its sensitivity to dynamic range issues, its most suitable use in the frame of biomarker discovery is not on very complex fl uids such as plasma, but rather on more proximal, simpler fl uids such as CSF, urine, or secretome samples. Here, we describe the complete work fl ow for the analysis of such dilute samples by two-dimensional electrophoresis, starting from sample concentration, then the two-dimensional electrophoresis step per se, ending with the protein detection by fl uorescence.
650 1 4 _a2D-PAGE
650 1 4 _aFLUORESCENCE DYES
650 1 4 _aIMAGE ANALYSIS
650 1 4 _aSAMPLE PREPARATION
650 1 4 _aSECRETOME
650 1 4 _aBIOLOGICAL FLUIDS
700 1 2 _aRabilloud, T.
700 1 2 _aTriboulet, S.
856 4 0 _uhttps://drive.google.com/file/d/12ri9PLUMgzsnG02apyrxOutBS8Dol3H2/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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