| 000 | 01556nam a2200361Ia 4500 | ||
|---|---|---|---|
| 003 | MX-MdCICY | ||
| 005 | 20250625153947.0 | ||
| 040 | _cCICY | ||
| 090 | _aB-14756 | ||
| 245 | 1 | 0 | _aVerticilide, a new ryanodine-binding inhibitor, produced byVerticilliumsp. FKI-1033 |
| 490 | 0 | _vThe Journal of Antibiotics , 63(2), p.77-82, 2010 | |
| 520 | 3 | _aA new ryanodine-binding inhibitor, verticilide, was isolated from the cultured broth of a fungus,Verticilliumsp. FKI-1033. It is a 24-membered ring cyclic depsipeptide, its structure being elucidated as cyclo[(2R)-2-hydroxyheptanoyl-N-methyl-L-alanyl]4. Verticilide inhibited ryanodine binding to ryanodine receptors in the cockroach at an IC50value of 4.2lM, whereas inhibition against mouse ryanodine receptors was weak (IC50ΒΌ53.9lM). | |
| 650 | 1 | 4 | _aDEPSIPEPTIDEINSECTICIDE |
| 650 | 1 | 4 | _aRYANODINE-BINDING INHIBITOR |
| 650 | 1 | 4 | _aRYANODINE RECEPTOR |
| 650 | 1 | 4 | _aVERTICILIDE |
| 650 | 1 | 4 | _aVERTICILLIUM |
| 700 | 1 | 2 | _aKazuro Shiomi |
| 700 | 1 | 2 | _aRyosuke Matsui |
| 700 | 1 | 2 | _aAtsuo Kakei |
| 700 | 1 | 2 | _aYuichi Yamaguchi |
| 700 | 1 | 2 | _aRokuro Masuma |
| 700 | 1 | 2 | _aHiroko Hatano |
| 700 | 1 | 2 | _aNoriko Arai |
| 700 | 1 | 2 | _aNoriko Arai |
| 700 | 1 | 2 | _aHaruo Tanaka |
| 700 | 1 | 2 | _aSusumu Kobayashi |
| 700 | 1 | 2 | _aAndreas Turberg |
| 700 | 1 | 2 | _aSatoshi Omura |
| 856 | 4 | 0 |
_uhttps://drive.google.com/file/d/1rMZvRk8qCBc0AJs-B86_1FrULqPSBGyw/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 |
_2Loc _cREF1 |
||
| 008 | 250602s9999 xx |||||s2 |||| ||und|d | ||
| 999 |
_c48941 _d48941 |
||