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090 _aB-14837
245 1 0 _aRetromer association with membranes Plants have their own rules!
490 0 _vPlant Signaling & Behavior, 8(9), p.e25312-1, 2013
520 3 _athe retromer is an endosome-localized complex involved in protein trafficking. to better understand its function and regulation in plants, we recently investigated how Arabidopsisretromer subunits assemble and are targeted to endosomal membranes and highlighted original features compared with mammals. We characterized Arabidopsis vps26 null mutant and showed that it displays severe developmental defaults similar to those observed in vps29mutant. here, we go further by describing new phenotypic defects associated with loss of VPS26function, such as inhibition of lateral root initiation. recently, we showed that VPS35 subunit plays a crucial role in the recruitment of the plant retromer to endosomes, probably through an interaction with the rab7 homolog raBG3f. in this work, we now show that contrary to mammals, Arabidopsis rab5 homologs do not seem to be necessary for the recruitment of the core retromer to endosomal membranes, which highlights a new specificity of the plant retromer.
650 1 4 _aRETROMER
650 1 4 _aARABIDOPSIS THALIANA
650 1 4 _aENDOSOMES
650 1 4 _aRAB GTPASES
650 1 4 _aPLANT DEVELOPMENT
700 1 2 _aZelazny, E.
700 1 2 _aSantambrogio, M.
700 1 2 _aGaude, T.
856 4 0 _uhttps://drive.google.com/file/d/19O8-xq93eo02wYU1wk2RGM3oWfKwdNTb/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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