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090			_aB-14931
245	1	0	_aA Comparison of Human Umbilical Cord Matrix Stem Cells and Temporomandibular Joint Condylar Chondrocytes for Tissue Engineering Temporomandibular Joint Condylar Cartilage
490	0		_vTissue Engineering, 13(8), p.2003-2010, 2007
520	3		_aThe temporomandibular joint (TMJ)presents many problems in modern musculoskeletal medicine. Pa-tients who suffer from TMJ disorders often experience amajor loss in quality of life due to the debilitating effects that TMJ disorders can have on everyday activities. Cartilage tissue engineering can lead to replacement tissues that could be used to treat TMJ disorders. In this study, a spinner flask was used for a period of 6 days to seed polyglycolic acid (PGA)scaffolds with either TMJ condylar chondrocytes or mesenchymal-like stem cells derived from human umbilical cord matrix (HUCM). Samples were then statically cultured for 4 weeks either in growth medium containing chondrogenic factors or in control medium. Immunohistochemical staining of HUCM constructs after 4 weeks revealed a strong presence of collagen I and minute amounts of collagen II, whereas TMJ constructs revealed little collagen I and no collagen II. The HUCM constructs were shown to contain more GAGs than the TMJ constructs quantitatively at week 0 and histologically at week 4. Moreover, the cellularity of HUCM constructs was 55
700	1	2	_aBailey, M.M.
700	1	2	_aLimin Wang, M.S.
700	1	2	_aBode, C.J.
700	1	2	_aMitchell, K.E.
700	1	2	_aDetamore, M.S.
856	4	0	_uhttps://drive.google.com/file/d/1bF1F4ZUzwbaP2cCgywi1k3misS41x7WX/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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