000			01741nam a2200193Ia 4500
003			MX-MdCICY
005			20250625160135.0
040			_cCICY
090			_aB-15593
245	1	0	_aThe Role of Plant Bax Inhibitor-1 in Suppressing H2O2 -Induced Cell Death
490	0		_vMethods in enzymology, 527, p.239-256, 2013
520	3		_aHydrogen peroxide (H2O2)is known to be a typical endogenous signaling molecule that triggers programmed cell death in plants and metazoan. In this respect, they seem to share the mechanism of cell death caused by H 2O and other reactive oxygen species (ROS). Bax inhibitor-1 (BI-1)is a well-conserved protein in plants and animals that serves as the inhibitor of mammalian proapoptotic proteins as well as plant ROS-induced cell death. As a target of H2O2 , mitochondrion is considered to be an organelle of the primary ROS generation and perception. Thus, analysis of mitochondrial behavior in relation to functional roles of regulatory proteins (e.g., BI-1)will lead us to understand the core mechanisms of cell death regulation conserved in eukaryotes. In this chapter, we first introduce techniques of analyzing H2O2- (and ROS-)mediated changes in mitochondrial behavior. Next, we describe our understanding of the functions of plant BI-1 in regulation of ROS-induced cell death, with a technical basis for assessment of tolerance to ROS-mediated cell death in model plant systems.
700	1	2	_aIshikawa, T.
700	1	2	_aUchimiya, H.
700	1	2	_aKawai-Yamada, M.
856	4	0	_uhttps://drive.google.com/file/d/1CyQIT7HzplqtUaWvwrZqPxYFjgHSW5N3/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942			_2Loc _cREF1
008			250602s9999 xx |||||s2 |||| ||und|d
999			_c49773 _d49773