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090 _aB-15907
245 1 0 _aAntifungal drugs: Targeting histone acetylation
490 0 _vNature Reviews Drug Discovery, 9, p.680-681, 2010
520 3 _aThe fungal pathogen Candida albicans causes serious infections in immunocompromised individuals, and although treatment is possible using azole or echinocandin drugs, their efficacy can be compromised by the emergence of drug-resistant strains. Writing in Nature Medicine, Wurtele and colleagues show that fungal enzymes that regulate histone acetylation - specifically the acetylation of lysine 56 on histone H3 (H3K56ac)- could be new targets for the treatment of C. albicans
650 1 4 _aCANDIDA ALBICANS
650 1 4 _aFUNGALS
650 1 4 _aPATHOGENS
700 1 2 _aHarrison, Charlotte
856 4 0 _uhttps://drive.google.com/file/d/14q9blOnZXpjZBB22Ghdd1Rei3qIyBsCJ/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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