000 01733nam a2200241Ia 4500
003 MX-MdCICY
005 20250625160143.0
040 _cCICY
090 _aB-16022
245 1 0 _aMolecular and multi-scale modelling methods of polymer device degradation
490 0 _vModelling Degradation of Bioresorbable Polymeric Medical Devices, October 10, p.201-231, 2014
520 3 _aThis chapter presents molecular models that can simulate microscopic polymer degradation behaviours instead of using phenomenological governing equations. Polymer details such as molecular weight distribution, end chain scission and random chain scission rates, and the copolymer ratio can be taken into account in the molecular models using the Kinetic Monte Carlo (KMC)method. A multi-scale model of the device degradation is also introduced in this chapter combining the molecular models and the macroscopic small molecule diffusion. The multi-scale model enables investigation of how local polymer properties affect bulk qualities over the entire device, which was not previously possible. In this chapter, the multi-scale model is also utilized to analyse experimental data, and correlations between detailed polymer properties and degradation rate are finalized. © 2015 Elsevier Ltd. All rights reserved.
650 1 4 _aDEGRADATION
650 1 4 _aDIFFUSION
650 1 4 _aKINETIC MONTE CARLO (KMC)
650 1 4 _aMODELLING
650 1 4 _aMOLECULAR MODELS
650 1 4 _aMULTI-SCALE
700 1 2 _aHan, X.
856 4 0 _uhttps://drive.google.com/file/d/1cK1zHnPqNCTzMrUJxeYOTv_mrCtIGrcp/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942 _2Loc
_cREF1
008 250602s9999 xx |||||s2 |||| ||und|d
999 _c50197
_d50197