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090 _aB-16084
245 1 0 _aChapter 3 Use of Bioinformatics in Planning a Protein Purification
490 0 _vMethods in Enzymology, 463(C), p.21-28, 2009
520 3 _aNow that many hundreds and even thousands of whole genomes have been sequenced, it is rare to be studying a target protein whose amino acid sequence is not known. However, it is still often necessary to obtain large amounts of the target protein for a variety of purposes including structural studies, drug discovery, enzymology, protein biochemistry, and industrial application. It would seem that knowing the amino acid sequences would make it much easier to design an effective purification of that protein. We examine in this chapter what you can and cannot predict from an amino acid sequence and conclude that protein purification is still largely an empirical science. © 2009 Elsevier Inc. All rights reserved
650 1 4 _aAMINO ACID SEQUENCE
650 1 4 _aBIOINFORMATICS
650 1 4 _aENZYMOLOGY
650 1 4 _aGENE SEQUENCE
650 1 4 _aGENOME
650 1 4 _aPRIORITY JOURNAL
650 1 4 _aPROTEIN ANALYSIS
650 1 4 _aPROTEIN PURIFICATION
650 1 4 _aPROTEIN STRUCTURE
650 1 4 _aREVIEW
650 1 4 _aALGORITHM
650 1 4 _aANIMAL
650 1 4 _aBIOLOGY
650 1 4 _aCHEMISTRY
650 1 4 _aHUMAN
650 1 4 _aHUMAN
650 1 4 _aMETABOLISM
650 1 4 _aMETHODOLOGY
650 1 4 _aPHYSIOLOGY
650 1 4 _aPROTEIN CONFORMATION
650 1 4 _aPROTEIN DENATURATION
650 1 4 _aPROTEIN MULTIMERIZATION
650 1 4 _aPROTEIN PROCESSING
700 1 2 _aBurgess, R.R.
856 4 0 _uhttps://drive.google.com/file/d/1oEkyjn6sC45wtg-j_AAv9ItyCreSafl3/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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