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090			_aB-16402
245	1	0	_aMaternal inheritance of mammalian mitochondrial DNA
490	0		_vNature, 251(5475), p.536-538, 1974
520	3		_aEUKARYOTIC cells contain a class of cytoplasmic DNA molecules which are found only within the mitochondria, where they replicate and are transcribed (for a general review see ref. 1). This mitochondrial DNA (mtDNA)constitutes the 'mitochondrial genome' and carries genetic information essential to mitochondrial function. In view of its extranuclear location, it is not surprising that inheritance of the mitochondrial genome is not governed by the same rules that apply to chromosomal genes. For fungi2-7 and amphibians8 there is evidence that the mitochondrial genome of an individual is derived solely from the maternal parent (in contrast to chromosomal genes, which are inherited biparentally). We present here evidence that the mitochondrial genome is inherited maternally in mammals too. © 1974 Nature Publishing Group.
650	1	4	_aANIMAL
650	1	4	_aCROSSES, GENETIC
650	1	4	_aDNA, MITOCHONDRIAL
650	1	4	_aELECTROPHORESIS, POLYACRYLAMIDE GEL
650	1	4	_aELECTROPHORESIS, STARCH GEL
650	1	4	_aEXTRACHROMOSOMAL INHERITANCE
650	1	4	_aFEMALE
650	1	4	_aGENOTYPE
650	1	4	_aHORSES
650	1	4	_aHYBRIDIZATION, GENETIC
650	1	4	_aLIVER
650	1	4	_aMALE
650	1	4	_aMYOCARDIUM
650	1	4	_aPERISSODACTYLA
650	1	4	_aPHENOTYPE
650	1	4	_aPHENOTYPE
700	1	2	_aHutchison Iii, C.A.
700	1	2	_aNewbold, J.E.
700	1	2	_aPotter, S.S.
700	1	2	_aEdgell, M.H.
856	4	0	_uhttps://drive.google.com/file/d/1VMqMqoo51wesks0qW6ovk8sDEsubL9V9/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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