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090 _aB-16689
245 1 0 _aBixin and norbixin in human plasma: Determination and study of the absorption of a single-dose of annatto food color
490 0 _vAnalyst, 122(9), p.977-980, 1997
520 3 _aA procedure was developed for the detection and determination of bixin and norbixin in human plasma by reversed-phase HPLC with a sensitivity limit of 5 µg l-1. A group of seven volunteers ingested a single dose of 1 ml of a commercial Annatto Food Color (16 mg of cis-bixin in soybean oil). The presence of bixin (cis and trans)and norbixin (cis and trans)was demonstrated in the plasma at average levels of 11.6, 10.1, 2.8 and 0 µg l-1 of bixin and 48, 58, 53 and 29 µg l-1 of norbixin after 2, 4, 6 and 8 h, respectively. Considerable individual variations were observed. Complete plasma clearance generally occurred for bixin by 8 h and for norbixin by 24 h after ingestion of cis-bixin.
650 1 4 _aBIXIN
650 1 4 _aCAROTENOIDS
650 1 4 _aHIGH-PERFORMANCE LIQUID CHROMATOGRAPHY
650 1 4 _aHUMAN PLASMA
650 1 4 _aINTESTINAL ADSORPTION
650 1 4 _aNORBIXIN
700 1 2 _aLevy, L.W.
700 1 2 _aRegalado, E.
700 1 2 _aNavarrete, S.
700 1 2 _aWatkins, R.H.
856 4 0 _uhttps://drive.google.com/file/d/1UDHHsLN1SqfvGzilK0LSzWNjyBbMqLK2/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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