| 000 | 01828nam a2200265Ia 4500 | ||
|---|---|---|---|
| 003 | MX-MdCICY | ||
| 005 | 20250625160207.0 | ||
| 040 | _cCICY | ||
| 090 | _aB-17266 | ||
| 245 | 1 | 0 | _aExtracellular matrix cell adhesion peptides: functional applications in orthopedic materials |
| 490 | 0 | _vTissue Engineering, 6(2), p.85-103, 2000 | |
| 520 | 3 | _aThis review describes research on selected peptide sequences that affect cell adhesion as it applies in orthopedic applications. Of particular interest are the integrin-binding RGD peptides and heparin-binding peptides. The influence of these peptides on cell adhesion is described. Cell adhesion is defined as a sequence of four steps: cell attachment, cell spreading, organization of an actin cytoskeleton, and formation of focal adhesions. RGD sequences clearly influence cell attachment and spreading, whereas heparin- binding sequences appear to be less efficient. Collectively, these sequences appear to promote all steps of cell adhesion in certain cell types. This review also addresses issues related to peptide immobilization, as well as potential complexities that may develop as a result of using these versatile cell-binding sequences. Also described are future directions in the field concerning use of existing and more sophisticated peptide substrata. | |
| 650 | 1 | 4 | _aACTIN |
| 650 | 1 | 4 | _aBINDING PROTEIN |
| 650 | 1 | 4 | _aBIOMATERIAL |
| 650 | 1 | 4 | _aCELL ADHESION MOLECULE |
| 650 | 1 | 4 | _aHEPARIN BINDING PROTEIN |
| 650 | 1 | 4 | _aINTEGRIN |
| 650 | 1 | 4 | _aPROTEOGLYCAN |
| 700 | 1 | 2 | _aLebaron, R. G. |
| 700 | 1 | 2 | _aAthanasiou, K. A. |
| 856 | 4 | 0 |
_uhttps://drive.google.com/file/d/1zcak6avDJ8hEUOyZ0GPTC2uejQ8lvbVV/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 |
_2Loc _cREF1 |
||
| 008 | 250602s9999 xx |||||s2 |||| ||und|d | ||
| 999 |
_c51429 _d51429 |
||