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245	1	0	_aRapid and reversible root growth inhibition by TIR1 auxin signalling.
490	0		_vNature Plants, 4(7), p. 453, 2018
520	3		_aThe phytohormone auxin is the information carrier in a plethora of developmental and physiological processes in plants1. It has been firmly established that canonical, nuclear auxin signalling acts through regulation of gene transcription2. Here, we combined microfluidics, live imaging, genetic engineering and computational modelling to reanalyse the classical case of root growth inhibition3 by auxin. We show that Arabidopsis roots react to addition and removal of auxin by extremely rapid adaptation of growth rate. This process requires intracellular auxin perception but not transcriptional reprogramming. The formation of the canonical TIR1/AFB-Aux/IAA co-receptor complex is required for the growth regulation, hinting to a novel, non-transcriptional branch of this signalling pathway. Our results challenge the current understanding of root growth regulation by auxin and suggest another, presumably non-transcriptional, signalling output of the canonical auxin pathway
700	1	2	_aFendrych, M.
700	1	2	_aAkhmanova, M
700	1	2	_aMerrin, J.
700	1	2	_aGlanc, M.
700	1	2	_aHagihara, S.
700	1	2	_aTakahashi, Uchida N.
700	1	2	_aTorii, K.
700	1	2	_aTorii, K.
856	4	0	_uhttps://drive.google.com/file/d/1IUOPbCDCq7AJuY-kqdE9bLa4Y4Z7H32o/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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