000			01929nam a2200241Ia 4500
003			MX-MdCICY
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040			_cCICY
090			_aB-17802
245	1	0	_aMetformin: a review of characteristics, properties, analytical methods and impact in the green chemistry.
490	0		_vCritical Reviews in analytical Chemistry, 48(1), p.66-72, 2018
520	3		_aDiabetes mellitus (DM)is considered a public health problem. The initial treatment consists of improving the lifestyle and making changes in the diet. When these changes are not enough, the use of medication becomes necessary. The metformin aims to reduce the hepatic production of glucose and is the preferred treatment for type 2. The objective is to survey the characteristics and properties of metformin, as well as hold a discussion on the existing analytical methods to green chemistry and their impacts for both the operator and the environment. For the survey, data searches were conducted by scientific papers in the literature as well as in official compendium. The characteristics and properties are shown, also, methods using liquid chromatography techniques, titration, absorption spectrophotometry in the ultraviolet and the infrared region. Most of the methods presented are not green chemistry oriented. It is necessary the awareness of everyone involved in the optimization of the methods applied through the implementation of green chemistry to determine the metformin.
650	1	4	_aANALYTICAL METHODS
650	1	4	_aDIABETES MELLITUS
650	1	4	_aGREEN CHEMISTRY
650	1	4	_aMETFORMIN
700	1	2	_aDa Trindade, M. T.
700	1	2	_aKogawa, A. C.
700	1	2	_aSalgado, H. R. N.
856	4	0	_uhttps://drive.google.com/file/d/1mL2Ltm2Bd1OJ-h9zz6DjFGvREgFsm5MB/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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