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090			_aB-17848
245	1	0	_aAntiproliferative activity and chemical constituents of Lonchocarpus cultratus (Fabaceae)
490	0		_vNatural Product Research, p.1-4, 2019
520	3		_aThe aerial parts of L. cultratus were submitted to a phytopharmacological investigation in order to isolate and identify the major secondary metabolites and evaluate its crude extract, fractions and isolated compounds for antiproliferative activity. Seven compounds were isolated and identified as the chalcones 2',4'-dihydroxy-5'-prenylchalcone (1)and isocordoin (2), the flavanone 8-prenylpinocembrin (3), the alkaloid 4-hydroxy-N-methylproline (4), the triterpenes lupeol and lupenone. These compounds were identified by nuclear magnetic resonance of 1H and 13C data in comparison with literature. Hexanic fraction and chalcone 2',4'-dihydroxy-5'-prenylchalcone showed potent results against human cancer cell lines tested.
650	1	4	_aLONCHOCARPUS CULTRATUS
650	1	4	_aANTIPROLIFERATIVE ACTIVITY
650	1	4	_aCHALCONES
650	1	4	_aFLAVONOIDS
700	1	2	_aDa Silva Landim, E. M.
700	1	2	_aRuiz, A. L. T.
700	1	2	_aDe Carvalho, J. E.
700	1	2	_aPomini, A. M.
700	1	2	_aPastorini, L. H.
700	1	2	_aOliveira Santin, S. M.
856	4	0	_uhttps://drive.google.com/file/d/1z9ODQNQkAlfay1eGJ-kfwC4J04ZWlpv7/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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