000			01564nam a2200313Ia 4500
003			MX-MdCICY
005			20250625160222.0
040			_cCICY
090			_aB-18040
245	1	0	_aBioactive luteoloside produced by Myroides odoratimimus, solvent-tolerant bacterium form the rhizosphere of Lonicera japonica.
490	0		_vNatural Product Research, 33(24), p.3559-3562, 2019
520	3		_aLuteoloside (luteolin-7-O-glucoside), the biomarker of Lonicera japonica, was efficiently bio-synthetized from its cheaper precursor luteolin. The structure of luteoloside was characterized by LC-MS and NMR analyses. Compared to the significant inhibitory effect of luteolin on human hepatocyte cell line LO2 at high doses, luteoloside did not show obvious cytotoxic effects at any test dose. Moreover, luteoloside exhibited obvious promotive effects on human hepatocyte cells, suggesting a potential application in hepatoprotective therapies.
650	1	4	_aMYROIDES ODORATIMIMUS
650	1	4	_aRHIZOSPHERE BACTERIA
650	1	4	_aLONICERA JAPÓNICA
650	1	4	_aBIOTRANSFORMATION
650	1	4	_aLUTEOLOSIDE
650	1	4	_aHEPATOCYTOTOXICITY
700	1	2	_aZhao, Y. X.
700	1	2	_aWang, J. J.
700	1	2	_aZhang, L.
700	1	2	_aZhang, S.
700	1	2	_aSu, S. L.
700	1	2	_aDuan, J. A.
700	1	2	_aXu, S. K.
856	4	0	_uhttps://drive.google.com/file/d/12wsGd1ADosUXcGDJoyoCnwpsEG_PNKfy/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942			_2Loc _cREF1
008			250602s9999 xx |||||s2 |||| ||und|d
999			_c52199 _d52199