000			01813nam a2200289Ia 4500
003			MX-MdCICY
005			20250625160223.0
040			_cCICY
090			_aB-18111
245	1	0	_aCRISPR/Cas9 for development of disease resistance in plants: recent progress, limitations and future prospects.
490	0		_vBriefings in Functional Genomics, 19(1), p.26-39, 2020
520	3		_aSeveral plant pathogens severely affect crop yield and quality, thereby threatening global food security. In order to cope with this challenge, genetic improvement of plant disease resistance is required for sustainable agricultural production, for which conventional breeding is unlikely to do enough. Luckily, genome editing systems that particularly clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein 9 (CRISPR/Cas9)has revolutionized crop improvement by enabling robust and precise targeted genome modifications. It paves the way towards new methods for genetic improvement of plant disease resistance and accelerates resistance breeding. In this review, the challenges, limitations and prospects for conventional breeding and the applications of CRISPR/Cas9 system for the development of transgene-free disease-resistant crops are discussed
650	1	4	_aGENOME EDITING
650	1	4	_aCRISPR/CAS9
650	1	4	_aDISEASE RESISTANCE
650	1	4	_aPHYTO-PATHOGENS
650	1	4	_aPLANT DISEASE
650	1	4	_aCROP IMPROVEMENT
700	1	2	_aAhmad, S.
700	1	2	_aWei, X.
700	1	2	_aSheng, Z.
700	1	2	_aHu, P.
700	1	2	_aTang, S.
856	4	0	_uhttps://drive.google.com/file/d/1dgDQxpbVMDVjTlleiV_o7OUVOWIXPUQY/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942			_2Loc _cREF1
008			250602s9999 xx |||||s2 |||| ||und|d
999			_c52269 _d52269