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| 003 | MX-MdCICY | ||
| 005 | 20250625160224.0 | ||
| 040 | _cCICY | ||
| 090 | _aB-18181 | ||
| 245 | 1 | 0 | _aEvolution and molecular mechanism of CRISPR/Cas9 systems. |
| 490 | 0 | _vIn Genome Engineering via CRISPR-Cas9 System. Academic Press., p.15-25, 2020 | |
| 520 | 3 | _aCRISPR/Cas module is an RNA-guided adaptive immune system, provides sequence-specific immunity against phages and (conjugative)plasmids. CRISPR/Cas system is basically categorized into three types: (type I, II and III), on the basis of effector complexes. CRISPR/Cas9 system is repercussion of evolutionary everlasting arm race between bacteria and phages. Molecular mechanism underlying the CRISPR system entails three distinct mechanistic stages: spacer acquisition, crRNA biogenesis and interference. CRISPR/Cas9 system composed of a combination of Cas9 (an endonuclease)and a customizable single guide RNA (sgRNA), the later directs the Cas9 for recognition and degradation of invading DNA. Furthermore, Cas9 and their ilk proteins with unique properties have opened a plethora of options including DNA/RNA genome targeting, transcription/translation regulation and empower researchers to edit genes with highly precision and speed. | |
| 650 | 1 | 4 | _aBACTERIA |
| 650 | 1 | 4 | _aCASCADE |
| 650 | 1 | 4 | _aCRISPR/CAS SYSTEMS |
| 650 | 1 | 4 | _aDCAS9 |
| 650 | 1 | 4 | _aGENOME EDITING |
| 650 | 1 | 4 | _aRNA |
| 700 | 1 | 2 | _aBhushan, K. |
| 856 | 4 | 0 |
_uhttps://drive.google.com/file/d/1OYdwUhuslep28rATaBWT__U21w7iUh83/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
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