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245	1	0	_aCaesalminaxins OT, cassane diterpenoids from the seeds of Caesalpinia minax and their anti-inflammation.
490	0		_vFitoterapia, 134, p.50-57, 2019
520	3		_aSix previously undescribed cassane diterpenoids, named caesalminaxins O-T (1-6), together with 28 known compounds (7-34), were isolated from the seeds of Caesalpinia minax Hance. Their structures, including their absolute configurations were elucidated by extensive spectroscopic analysis, X-ray diffraction, and quantum chemical calculations. Among the undescribed diterpenoids, compound 6 that possessed an unusual enol group at C-7 with a highly deshielded 1H NMR signal was the first example in cassane diterpenoids. All of the isolates were evaluated for their inhibitory activity against lipopolysaccharide-activated NO production in RAW264.7 cells. Compound 16 showed moderate inhibitory activity with an IC50 value of 17.3??M, which was more potent than the positive control (indomethacin, IC50?=?29.7??M).
650	1	4	_aCAESALPINIA MINAX
650	1	4	_aCASSANE DITERPENOIDS
650	1	4	_aANTI-INFLAMMATORY ACTIVITY
650	1	4	_aENOL GROUP
700	1	2	_aRuan, Q. F.
700	1	2	_aZhou, X. H.
700	1	2	_aJiang, S. Q.
700	1	2	_aYang, B.
700	1	2	_aJin, J.
700	1	2	_aCui, H.
700	1	2	_aZhao, Z. X.
856	4	0	_uhttps://drive.google.com/file/d/1-MlZYsK0iNStlpIBD6iekWw-vt-uu2RS/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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