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245 1 0 _aCRISPR/Cas9: A magic bullet to deal with plant viruses.
490 0 _vIn Plant Virus-Host InteractionIn Plant Virus-Host Interaction, p.443-460, 2021
520 3 _aViral diseases affect crops productivity thereby threatening world food security. For sustainable agriculture, disease resistance should be developed at genetic level. Advancements in the field of genome editing technologies have empowered us to create designer crops with desired traits. CRISPR/Cas is the most promising tool to create site specific modifications. The CRISPR-Cas genome editing platform comprises of a sequence-specific endonuclease such as Streptococcus pyogenes Cas9 (SpCas9), and a guide RNA molecules that directs the target specificity of the nucleases. This genome editing platform has been pragmatically harnessed to engineer virus resistance in plants. Specific regions of the viral genome involved in the viral replication can be targeted to restrain the peril of devastating plant viruses. Furthermore the system is amenable to multiplexing to target multiple DNA viruses.
650 1 4 _aCRISPER/CAS
650 1 4 _aPLANT VIRAL DISEASES
650 1 4 _aRESISTANCE
650 1 4 _aGENOME EDITING
650 1 4 _aZINC FINGER NUCLEASES
650 1 4 _aTRANSCRIPTIONAL ACTIVATOR LIKE EFFECTOR NUCLEASES
650 1 4 _aGUIDE RNA
650 1 4 _aNON HOMOLOGUS END JOINING
650 1 4 _aGEMINIVIRUSES
650 1 4 _aPOTTYVIRUSES
700 1 2 _aSingroha, G.
700 1 2 _aGupta, O. P.
700 1 2 _aGaur, R. K.
700 1 2 _aSharma, P.
856 4 0 _uhttps://drive.google.com/file/d/1eYGioek6Kdt0PUl-ifOkMI_XRVKMvDiP/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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