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245 1 0 _aBiological effects of essential oils - A review
490 0 _vFood and Chemical Toxicology, 46, p.446-475, 2008
520 3 _aSince the middle ages, essential oils have been widely used for bactericidal, virucidal, fungicidal, antiparasitical, insecticidal, medicinal and cosmetic applications, especially nowadays in pharmaceutical, sanitary, cosmetic, agricultural and food industries. Because of the mode of extraction, mostly by distillation from aromatic plants, they contain a variety of volatile molecules such as terpenes and terpenoids, phenol-derived aromatic components and aliphatic components. In vitro physicochemical assays characterise most of them as antioxidants. However, recent work shows that in eukaryotic cells, essential oils can act as prooxidants affecting inner cell membranes and organelles such as mitochondria. Depending on type and concentration, they exhibit cytotoxic effects on living cells but are usually nongenotoxic. In some cases, changes in intracellular redox potential and mitochondrial dysfunction induced by essential oils can be associated with their capacity to exert antigenotoxic effects. These findings suggest that, at least in part, the encountered beneficial effects of essential oils are due to prooxidant effects on the cellular level.
650 1 4 _aESSENTIAL OIL
650 1 4 _aCYTOTOXICITY
650 1 4 _aGENOTOXICITY
650 1 4 _aANTIGENOTOXICITY
650 1 4 _aPROOXIDANT ACTIVITY
700 1 2 _aBakkali, F.
700 1 2 _aAverbeck, S.
700 1 2 _aAverbeck, D.
700 1 2 _aIdaomar, M.
856 4 0 _uhttps://drive.google.com/file/d/1xGcx3Ouuj7opMZmwtnECbSRTmIQfOHwx/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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