000 02542nam a2200253Ia 4500
003 MX-MdCICY
005 20250625162419.0
040 _cCICY
090 _aB-18808
245 1 0 _aDetermination of chlorophylls in Taraxacum formosanum by high-performance liquid chromatography-diode array detection-mass spectrometry and preparation by column chromatography
490 0 _vJournal of agricultural and Food Chemistry, 60(24), p.6108-6115, 2012
520 3 _aTaraxacum formosanum, a well-known Chinese herb shown to be protective against hepatic cancer as well as liver and lung damage, may be attributed to the presence of abundant carotenoids and chlorophylls. However, the variety and content of chlorophylls remain uncertain. The objectives of this study were to develop an high-performance liquid chromatography? diode array detection?mass spectrometry method for determination of chlorophylls in T. formosanum and preparation by column chromatography. An HyPURITY C18 column and a gradient mobile phase of water (A), methanol (B), acetonitrile (C), and acetone (D)could resolve 10 chlorophylls and an internal standard Fast Green FCF within 30 min with a flow rate at 1 mL/ min and detection at 660 nm. Both chlorophylls a and a? were present in the largest amount (1389.6 ?g/g), followed by chlorophylls b and b? (561.2 ?g/g), pheophytins a and a? (31.7 ?g/g), hydroxychlorophyll b (26.5 ?g/g), hydroxychlorophylls a and a? (9.8 ?g/g), and chlorophyllides a and a? (0.35 ?g/g). A glass column containing 52 g of magnesium oxide?diatomaceous earth (1:3, w/w)could elute chlorophylls with 800 mL of acetone containing 50 percent ethanol at a flow rate of 10 mL/min. Some new chlorophyll derivatives including chlorophyllide b, pyropheophorbide b, hydroxypheophytin a, and hydroxypheophytin a? were generated during column chromatography but accompanied by a 63 percent loss in total chlorophylls. Thus, the possibility of chlorophyll fraction prepared from T. formosanum as a raw material for future production of functional food needs further investigation.
650 1 4 _aTARAXACUM FORMOSANUM
650 1 4 _aCHLOROPHYLLS
650 1 4 _aHPLC-DAD-MS
650 1 4 _aCOLUMN CHROMATOGRAPH
700 1 2 _aLoh, C. H.
700 1 2 _aInbaraj, B. S.
700 1 2 _aLiu, M. H.
700 1 2 _aChen, B. H.
856 4 0 _uhttps://drive.google.com/file/d/1jlxpT5xanF7Y9JOdFlF_A5-vCcDGojcK/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942 _2Loc
_cREF1
008 250602s9999 xx |||||s2 |||| ||und|d
999 _c52954
_d52954