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090			_aB-18824
245	1	0	_aFrom genome scissors to molecular scalpel: evolution of CRISPR systems.
490	0		_vBiotechnology and Genetic Engineering Reviews, 37(1), p.82-104, 2021
520	3		_aFrom bizarre palindromic repeats to a bacterial defense mechanism, to genome editing tool, and more, Clustered Regularly Interspaced Short Palindromic Repeats or CRISPR has significantly impacted the way we study genome modification in less than a decade. In this review, we would like to highlight some key players over 30 years of research and explain this biotechnological tool's basic mechanisms. We also refer to the evolution of the CRISPR variants and some of the applications derived from them. The understanding and upgrading of this system will be a valuable tool in the years to come to solve some of the challenges in diverse fields from pharmaceuticals to therapeutics, from basic plant genetics to crop improvement, from metabolic engineering to waste management and industrial processing.
650	1	4	_aCRISPR
650	1	4	_aGENOME EDITING
650	1	4	_aNUCLEASES
700	1	2	_aGuzmán-Zapata, D.
700	1	2	_aVargas-Morales, B. V.
700	1	2	_aLoyola-Vargas, V. M.
856	4	0	_uhttps://drive.google.com/file/d/1HWz9AlpfHPhJECUAA9Q8PtK83u2Xt7zX/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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