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040			_cCICY
090			_aB-18917
245	1	0	_aTwo new P-coumaroyl flavonoid glycosides having Cytokine increasing activity from Centaurium spicatum L
490	0		_vPhytoChemistry Letters, 17, p.144-151, 2016
520	3		_aTwo new P-coumaroyl flavonol glycosides, Kaempferol 3-O-[?-D-glucopyranosyl- (1 ? 4)-?-l-rhamnopyranosyl-(1 ? 4)-?-l-rhamnopyranosyl-(1 ? 6)-(4 trans- P-coumaroyl)]-?-D- galactopyranoside (1)and Quercetin 3-O-[?-D-glucopyranosyl-(1 ? 4)-?-l-rhamnopyranosyl-(1 ? 4)-?-l-rhamnopyranosyl-(1 ? 6)-(4 trans- P-coumaroyl)]-?-D-galactopyranoside (2)were isolated from the aerial part of Centaurium spicatum (L.)Fritsch (Gentianaceae). Structure elucidation of the new compounds was established on the basis of 1D and 2D NMR analyses including 1H, 13C NMR, DEPT-135 NMR, Hsingle bondH COSY, HMQC and HMBC experiments. In addition to HRFAB Mass Spectrometry. Also it is noted that these new compounds significantly increase both TNF-? and IL-1? after 48 h of treatment (this level of increase of cytokines (300/200)activates the cytokines like vaccines towards invasion of microorganisms).
650	1	4	_aCENTAURIUM SPICATUM
650	1	4	_aGENTIANACEAE
650	1	4	_aFLAVONOID GLYCOSIDES
650	1	4	_aP-COUMAROYL
650	1	4	_aCYTOKINE INCREASE ACTIVITY
700	1	2	_aAllam, A. E.
700	1	2	_aNafady, A. M.
700	1	2	_aHassanein, A. M.
700	1	2	_aMostafa, M. A.
700	1	2	_aEl-Shanawany, M. A.
700	1	2	_aTakano, F.
700	1	2	_aOhta, T.
856	4	0	_uhttps://drive.google.com/file/d/1mFyKyr-mK064gRiHKJJV4NRDs-mGD4kx/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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