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090 _aB-19174
245 1 0 _aBacterial biofilms associated skin disorders: Pathogenesis, advanced pharmacotherapy and nanotechnology-based drug delivery systems as a treatment approach
490 0 _vLife Sciences, 287, p.120148, 2021
520 3 _aBiofilms are microcolonies of microbes that form communities with a variety of microbes, exhibit the same gene composition but differ in gene expression. Biofilm-associated infections have been in existence for a long, however, biofilm-associated skin disorders have not been investigated much. Objectives. Biofilms, which are made mostly of the matrix can be thought of as communities of microbes that are more virulent and more difficult to eradicate as compared to their planktonic counterparts. Currently, several formulations are available in the market which have the potential to treat biofilm-assisted skin disorders. However, the existing pharmacotherapies are not competent enough to cure them effectively and entirely, in several cases. Especially with the rising resistance towards antibiotics, it has become particularly challenging to ameliorate these disorders completely. The new approaches are being used to combat biofilm-associated skin disorders, some of them being photodynamic therapy, nanotherapies, and the use of novel drug delivery systems. The focus of attention, however, is nanotherapy. Micelles, solid lipid nanoparticles, quatsomes, and many others are being considered to find a better solution for the biofilm-associated skin disorders.
650 1 4 _aBIOFILMS
650 1 4 _aSKIN DISORDERS
650 1 4 _aNANOTECHNOLOGY
650 1 4 _aPHARMACOTHERAPY
650 1 4 _aSOLID LIPID NANOPARTICLES
650 1 4 _aQUATSOMES
700 1 2 _aVyas, T.
700 1 2 _aRapalli, V. K.
700 1 2 _aChellappan, D. K.
700 1 2 _aDua, K.,
700 1 2 _aDubey, S. K.
700 1 2 _aSinghvi, G.
856 4 0 _uhttps://drive.google.com/file/d/1WjACB4sEanEnH559Ik5hggokBpoXosXL/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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