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090			_aB-19264
245	1	0	_aChanges in denaturation and rheological properties of collagen-hyaluronic acid scaffolds as a result of temperature dependencies
490	0		_vInternational Journal of Biological Macromolecules, 36(5), p.299-304, 2005
520	3		_aThis report describes the effect of temperature on the mechanical viscoelastic properties such as: storage modulus (E?), loss modulus (E?), and loss tangent (tan ?)of the collagen sponges modified with hyaluronic acid (HA). In order to detect collagen-HA copolymer denaturation and to assess its thermal stability, the differential scanning calorimetry (DSC)supplemented by thermogravimetric (TG)measurements was used. The denaturation temperature (Td)of unmodified collagen samples increased from 69 to 86 °C for cross-linked samples, respectively. These temperature dependencies show remarkable changes in E? and E? at selected temperature up to 226 °C for all samples due to the release of loosely and strongly bound water. The influence of HA on the viscoelastic behavior of collagen is manifested by a shift of the tan ? peak associated with the process of decomposition towards higher temperatures resulting in a higher thermo-stability of the modified scaffolds.
650	1	4	_aCOLLAGEN
650	1	4	_aHYALURONIC ACID
650	1	4	_aTHERMAL STABILITY
700	1	2	_aPietrucha, K.
856	4	0	_uhttps://drive.google.com/file/d/1jsAq9CZvxrwFsA7PjIKZQzjqF_avgxeZ/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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