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090 _aB-19518
245 1 0 _aA comparative study of three-dimensional printing directions: The degradation and toxicological profile of a PLA/PHA blend
490 0 _vPolymer degradation and stability, 152, p.191-207, 2018
520 3 _aThe use of biobased plastics is of great importance for many applications. Blending thermoplastic polylactide (PLA)with polyhydroxyalkanoate (PHA)enables the formulation of a more mechanically powerful material and this enables tailored biodegradation properties. In this study we demonstrate the 3D printing of a PLA/PHA blend as a potential candidate for biocompatible material applications. The filament for 3D printing consisted of PHA, which contains predominantly 3-hydroxybutyrate units and a small amount of 3-hydroxyvalerate units, as revealed by multistage mass spectrometry (ESI-MSn). This research found that the properties of 3D printed species before and during abiotic degradation are dependent on printing orientation. Furthermore, the 3D printed specimens exhibited good biocompatibility with HEK293?cells, indicating real promise as biological scaffolds for tissue engineering applications.
650 1 4 _aTHREE-DIMENSIONAL PRINTING
650 1 4 _aLAYER ORIENTATION
650 1 4 _aDEGRADATION
650 1 4 _a(BIO)DEGRADABLE POLYESTER
650 1 4 _aTOXICITY TEST
650 1 4 _aCELL PROLIFERATION
700 1 2 _aAusejo, J. G.
700 1 2 _aRydz, J.
700 1 2 _aMusiol, M.
700 1 2 _aSikorska, W.
700 1 2 _aSobota, M.
700 1 2 _aWlodarczyk, J.
700 1 2 _aKowalczuk, M.
856 4 0 _uhttps://drive.google.com/file/d/1BD9pcny9RgB2rkeWB2bQjC9xUwxZgHr_/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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