000			02060nam a2200253Ia 4500
003			MX-MdCICY
005			20250625162433.0
040			_cCICY
090			_aB-19574
245	1	0	_aAmino acids - A life between metabolism and signaling
490	0		_vPlant Science, 229, p.225-237, 2014
520	3		_amolecules in mammalians and plants. This review is focused on new insights, or speculations, on signaling functions of serine, _-aminobutyric acid (GABA)and phenylalanine-derived phenylpropanoids. Serine acts as signal in brain tissue and mammalian cancer cells. In plants, de novo serine biosynthesis is also highly active in fast growing tissues such as meristems, suggesting a similar role of serine as in mam-malians. GABA functions as inhibitory neurotransmitter in the brain. In plants, GABA is also abundant and seems to be involved in sexual reproduction, cell elongation, patterning and cell identity. The aro-matic amino acids phenylalanine, tyrosine, and tryptophan are precursors for the production of secondary plant products. Besides their pharmaceutical value, lignans, neolignans and hydroxycinnamic acid amides (HCAA)deriving from phenylpropanoid metabolism and, in the case of HCAA, also from arginine have been shown to fulfill signaling functions or are involved in the response to biotic and abiotic stress. Although some basics on phenylpropanoid-derived signaling have been described, little is known on recognition- or signal transduction mechanisms. In general, mutant- and transgenic approaches will be helpful to elucidate the mechanistic basis of metabolite signaling.
650	1	4	_aSERINE
650	1	4	_aGABA
650	1	4	_aNEOLIGNANS
650	1	4	_aHYDROXYCINNAMIC-ACID-AMIDES
650	1	4	_aSIGNALING
700	1	2	_aHausler, R.E.
700	1	2	_aLudewig, F.
700	1	2	_aKrueger, K.
856	4	0	_uhttps://drive.google.com/file/d/1ai_6Ov1RtbpVpVebDqt5LE0vRGkgz92S/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942			_2Loc _cREF1
008			250602s9999 xx |||||s2 |||| ||und|d
999			_c53698 _d53698