000			01733nam a2200265Ia 4500
003			MX-MdCICY
005			20250625162439.0
040			_cCICY
090			_aB-19898
245	1	0	_apH-dependent hydrophobicity of the cyanobacteria toxin microcystin-LR
490	0		_vWater Research, 33(3), p.677-680, 1999
520	3		_aAlthough the presence of hepatotoxins in surface and drinking water is regarded as an ecotoxicological and human health problem, limited knowledge exists on the fate of these compounds. Therefore the n-octanol/water distribution ratio (Dow)of the hepatotoxin microcystin-LR (MC-LR)was determined in order to enable the prediction of the fate of this compound in the aquatic environment. The presence of two free ionizable carboxyl groups and one free ionizable amino group in MC-LR suggest that its speciation and partitioning between octanol and water is pH dependent. This was experimentally studied and confirmed in the present study. The log Dow of MC-LR decreased from 2.18 at pH=1 to ?1.76 at pH=10. From the low log Dow values, especially at the basic pH region at which the toxin producing cyanobacteria flourish, a low tendency to bioconcentrate from water in biota can be expected.
650	1	4	_aMICROCYSTIN-LR
650	1	4	_aCYANOBACTERIA
650	1	4	_aN-OCTANOL/WATER DISTRIBUTION RATIO
650	1	4	_aPH
650	1	4	_aBIOCONCENTRATION
700	1	2	_aDe Maagd, P. G. J.
700	1	2	_aHendriks, A. J.
700	1	2	_aSeinen, W.
700	1	2	_aSijm, D. T.
856	4	0	_uhttps://drive.google.com/file/d/1mIpIFT9TcYg3e6QJRvC-YIqoFp2CxBI8/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942			_2Loc _cREF1
008			250602s9999 xx |||||s2 |||| ||und|d
999			_c54005 _d54005