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090 _aB-20012
245 1 0 _a3D printing strategies for peripheral nerve regeneration
490 0 _vBiofabrication, 10(3), p.032001, 2018
520 3 _aAfter many decades of biomaterials research for peripheral nerve regeneration, a clinical product (the nerve guide), is emerging as a proven alternative for relatively short injury gaps. This review identifies aspects where 3D printing can assist in improving long-distance nerve guide regeneration strategies. These include (1)3D printing of the customizable nerve guides, (2)fabrication of scaffolds that fill nerve guides, (3)3D bioprinting of cells within a matrix/bioink into the nerve guide lumen and the (4)establishment of growth factor gradients along the length a nerve guide. The improving resolution of 3D printing technologies will be an important factor for peripheral nerve regeneration, as fascicular-like guiding structures provide one path to improved nerve guidance. The capability of 3D printing to manufacture complex structures from patient data based on existing medical imaging technologies is an exciting aspect that could eventually be applied to treating peripheral nerve injury. Ultimately, the goal of 3D printing in peripheral nerve regeneration is the automated fabrication, potentially customized for the patient, of structures within the nerve guide that significantly outperform the nerve autograft over large gap injuries.
650 1 4 _aADDITIVE MANUFACTURING
650 1 4 _aNERVE GUIDES
650 1 4 _aNERVE CONDUITS
650 1 4 _aNEURAL TISSUE ENGINEERING
700 1 2 _aPetcu, E. B.
700 1 2 _aMidha, R.
700 1 2 _aMccoll, E.
700 1 2 _aPopa-Wagner, A.
700 1 2 _aChirila, T. V.
700 1 2 _aDalton, P. D.
856 4 0 _uhttps://drive.google.com/file/d/1WBdIU6-aNnzAOzFgqHTBl5NY7ww6yl1L/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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