000			01891nam a2200289Ia 4500
003			MX-MdCICY
005			20250625162441.0
040			_cCICY
090			_aB-20051
245	1	0	_aABCB-mediated shootward auxin transport feeds into the root clock
490	0		_vEMBO Reports, p.e56271, 2023
520	3		_aAlthough strongly influenced by environmental conditions, lateral root (LR)positioning along the primary root appears to follow obediently an internal spacing mechanism dictated by auxin oscillations that prepattern the primary root, referred to as the root clock. Surprisingly, none of the hitherto characterized PIN- and ABCB-type auxin transporters seem to be involved in this LR prepatterning mechanism. Here, we characterize ABCB15, 16, 17, 18, and 22 (ABCB15-22)as novel auxin-transporting ABCBs. Knock-down and genome editing of this genetically linked group of ABCBs caused strongly reduced LR densities. These phenotypes were correlated with reduced amplitude, but not reduced frequency of the root clock oscillation. High-resolution auxin transport assays and tissue-specific silencing revealed contributions of ABCB15-22 to shootward auxin transport in the lateral root cap (LRC)and epidermis, thereby explaining the reduced auxin oscillation. Jointly, these data support a model in which LRC-derived auxin contributes to the root clock amplitude.
650	1	4	_aABCB
650	1	4	_aAUXIN TRANSPORT
650	1	4	_aLATERAL ROOT
650	1	4	_aROOT MERISTEM
700	1	2	_aChen, J.
700	1	2	_aHu, Y.
700	1	2	_aHao, P.
700	1	2	_aTsering, T.
700	1	2	_aXia, J.
700	1	2	_aZhang, Y.
700	1	2	_aVanneste, S.
856	4	0	_uhttps://drive.google.com/file/d/1rwgzILP6Fp5uxyzbFaXoyOxtrxbK1Tij/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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