000			02107nam a2200301Ia 4500
003			MX-MdCICY
005			20250625162443.0
040			_cCICY
090			_aB-20142
245	1	0	_aEnhanced profiling and quantification of ginsenosides from mountain-cultivated ginseng and comparison with garden-cultivated ginseng
490	0		_vJournal of Chromatography A, 1692, p.463826, 2023
520	3		_aPanax ginseng can be generally divided into mountain-cultivated ginseng (MCG)and garden-cultivated ginseng (GCG). The market price of MCG is significantly higher than that of GCG. However, the chemical compositions of MCG and the differences from GCG remained unclear. In this study, an integrated strategy combing an offline two-dimensional liquid chromatography separation, LTQ-orbitrap dual mode acquisition, and Q-trap full quantification/quasi-quantification was proposed to explore and compare the chemical compositions of MCG. Consequently, 559 ginsenosides were characterized, among which 437 ginsenosides were in-depth characterized with ?-chain and ?-chain annotated. Subsequently, enhanced quantification of 213 ginsenosides was conducted in 57 batches of MCG and GCG. Ginsenosides were found more abundant in MCG than GCG. In addition, 25-year-old MCG could be distinctly differentiated from 15/20-year-old MCG. This strategy facilitated the enhanced profiling and comparison of ginsenosides, improved the quality control tactics of MCG and provided a reference approach for other ginseng related products.
650	1	4	_aCHEMICAL CHARACTERIZATION
650	1	4	_aGINSENOSIDES
650	1	4	_aMOUNTAIN-CULTIVATED GINSENG
650	1	4	_aPRECURSOR ION LIST
650	1	4	_aQUASI-QUANTIFICATION
700	1	2	_aQu, H.
700	1	2	_aWang, J.
700	1	2	_aYao, C.
700	1	2	_aWei, X.
700	1	2	_aWu, Y.
700	1	2	_aCheng, M.
700	1	2	_aGuo, D. A.
856	4	0	_uhttps://drive.google.com/file/d/13P-56ckhfSD1EYceChR-WcTcLVFS3DEg/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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