000			02110nam a2200253Ia 4500
003			MX-MdCICY
005			20250625162446.0
040			_cCICY
090			_aB-20289
245	1	0	_aGlutamine metabolism, sensing, and signaling in plants
490	0		_vPlant & Cell Physiology, 10.1093/pcp/pcad054, 2023
520	3		_aGlutamine (Gln)is the first amino acid synthesized in nitrogen (N)assimilation in plants. Gln synthetase (GS), converting glutamate (Glu)and NH4+ into Gln at the expense of ATP, is one of the oldest enzymes in all life domains. Plants have multiple GS isoenzymes that work individually or cooperatively to ensure the Gln supply is sufficient for plant growth and development under various conditions. Gln is a building block for protein synthesis and an N-donor for the biosynthesis of amino acids, nucleic acids, amino sugars, and vitamin B coenzymes. Most reactions using Gln as an N-donor are catalyzed by Gln amidotransferase (GAT)that hydrolyzes Gln to Glu and transfers the amido group of Gln to an acceptor substrate. Several GAT domain-containing proteins of unknown function in the reference plant Arabidopsis thaliana suggest that some metabolic fates of Gln have yet to be identified in plants. In addition to metabolism, Gln signaling has emerged in recent years. The N regulatory protein PII senses Gln to regulate arginine biosynthesis in plants. Gln promotes somatic embryogenesis and shoot organogenesis with unknown mechanisms. Exogenous Gln has been implicated in activating stress and defense responses in plants. Likely, Gln signaling is responsible for some of the new Gln functions in plants.
650	1	4	_aGLUTAMINE
650	1	4	_aGLUTAMINE AMIDOTRANSFERASE
650	1	4	_aGLUTAMINE SYNTHETASE
650	1	4	_aMETABOLISM
650	1	4	_aSIGNALING
700	1	2	_aLee, K. T.
700	1	2	_aLiao, H. S.
700	1	2	_aHsieh, M. H.
856	4	0	_uhttps://drive.google.com/file/d/18l4yT_0SnQc83fMxIle25iqAGvLsyJTR/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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