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245 1 0 _aAntifungal and synergistic activities of some selected essential oils on the growth of significant indoor fungi of the genus Aspergillus
490 0 _vJournal of Environmental Science and Health, Part A, 56(12), p.1335-1346, 2021
520 3 _aThe study aimed to assess the antifungal activity of twenty-five essential oils (EOs)and the potential synergistic activity of the most effective EOs against significant indoor fungi of the genus Aspergillus [A. fumigatus (KBio-122), A. flavus (KBio-134), A. terreus (KBio-145)and A. niger (KBio-202)]. The chemical composition of all EOs was evaluated by the gas chromatography coupled with mass spectrometry (GC/MS)and gas chromatography with flame ionization detector (GC-FID)analysis. The antifungal susceptibility of EOs was evaluated by using the broth microdilution method. The most effective EOs were selected to determine the minimum inhibitory concentrations (MICs)and minimum fungicidal concentrations (MFCs)at a concentration range from 256 to 0.125 ?g/mL. For the synergistic activities, the most effective EOs were tested using the chessboard pattern. The most sensitive strain to treatments with essential oils alone and in the combination of EOs was A. flavus (KBio-134). The chessboard assay showed that combinations of lemongrass and thyme EOs proved the most potent synergistic antifungal activity (FICI = 0.1875)against A. fumigatus (KBio-122). The synergy displayed by a combination of some EOs may be used to control fungal growth or increasing resistance to available synthetic antifungals, consequently permitting the reduction of their most active doses.
650 1 4 _aANTIFUNGAL ACTIVITY
650 1 4 _aASPERGILLUS
650 1 4 _aESSENTIAL OILS
650 1 4 _aIN VITRO
650 1 4 _aSYNERGISM
700 1 2 _aHlebová, M.
700 1 2 _aHleba, L.
700 1 2 _aMedo, J.
700 1 2 _aKovácik, A.
700 1 2 _aCubon, J.
700 1 2 _aIvana, C.
700 1 2 _aKloucek, P.
856 4 0 _uhttps://drive.google.com/file/d/1kiDf34mH631Ck-2W8IzNKptqNtDXW6BK/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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