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005			20250625162451.0
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090			_aB-20548
245	1	0	_aAdvances in DNA methylation and demethylation in medicinal plants: a review
490	0		_vMolecular Biology Reports, 50(9), p.7783-7796, 2023
520	3		_aDNA methylation and demethylation are widely acknowledged epigenetic phenomena which can cause heritable and phenotypic changes in functional genes without changing the DNA sequence. They can thus affect phenotype formation in medicinal plants. However, a comprehensive review of the literature summarizing current research trends in this field is lacking. Thus, this review aims to provide an up-to-date summary of current methods for the detection of 5-mC DNA methylation, identification and analysis of DNA methyltransferases and demethyltransferases, and regulation of DNA methylation in medicinal plants. The data showed that polyploidy and environmental changes can affect DNA methylation levels in medicinal plants. Changes in DNA methylation can thus regulate plant morphogenesis, growth and development, and formation of secondary metabolites. Future research is required to explore the mechanisms by which DNA methylation regulates the accumulation of secondary metabolites in medicinal plants.
650	1	4	_aDNA DEMETHYLASES
650	1	4	_aDNA METHYLATION
650	1	4	_aDNA METHYLTRANSFERASES
650	1	4	_aMEDICINAL PLANTS
650	1	4	_aSECONDARY METABOLITES
700	1	2	_aZang, Y.
700	1	2	_aXie, L.
700	1	2	_aSu, J.
700	1	2	_aLuo, Z.
700	1	2	_aJia, X.
700	1	2	_aMa, X.
856	4	0	_uhttps://drive.google.com/file/d/1ucn7WWCDYX_VUoLtoZcbUqz7CeGfPaf0/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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