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090 _aB-20588
245 1 0 _aA validated 1H NMR method for the determination of the degree of deacetylation of chitosan
490 0 _vJournal of Pharmaceutical and Biomedical Analysis, 32(6), p.1149-1158, 2003
520 3 _aA method for the determination of the degree of deacetylation (DDA)of chitosan by 1H NMR spectroscopy has been formally validated. Chitosans with DDA ranging from 48 to 100 percent have been used for the validation. The method is found to be simple, rapid and more precise than other known techniques like IR or titration for percentDDA measurements. The precision, ruggedness, robustness, specificity, stability and accuracy of the technique are discussed in this paper.
650 1 4 _aCHITOSAN
650 1 4 _aCHITIN
650 1 4 _aPH-SENSITIVE
650 1 4 _aIR
650 1 4 _a1H NMR
650 1 4 _aDEGREE OF DEACETYLATION
700 1 2 _aLavertu, M.
700 1 2 _aXia, Z.
700 1 2 _aSerreqi, A. N.
700 1 2 _aBerrada, M.
700 1 2 _aRodrigues, A.
700 1 2 _aWang, D.
700 1 2 _aGupta, A.
856 4 0 _uhttps://drive.google.com/file/d/1Hx3yRGU3DkqkfjyQms4HxrE23NyeNre7/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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