000 02407nam a2200301Ia 4500
003 MX-MdCICY
005 20250625162452.0
040 _cCICY
090 _aB-20626
245 1 0 _aGenome-wide characterization of NBS-LRR family genes and expression analysis under powdery mildew stress in Lagenaria siceraria
490 0 _vPhysiological and Molecular Plant Pathology, 118, p.101798, 2022
520 3 _aAs the largest group of plant resistance genes, the nucleotide-binding site-leucine-rich repeat (NBS-LRR)genes play a critical role in plant disease defense system. The bottle gourd is a distinctive horticultural crop of the Cucurbitaceae family and powdery mildew is one of the major diseases jeopardizing crop production and quality. In this study, we have identified 84 NBS-LRR genes and divided into seven subfamilies. Phylogenetic tree and motif analysis grouped these genes into two major clusters with toll/interleukin-1 like receptor (TIR)domain or a coiled-coil domain. Subsequently, duplication events, motif sequence, orthologous gene cluster, protein-protein interaction, cis-elements were analyzed. 12 pairs of tandem duplicated genes and two pairs of segmental duplicated genes were detected in NBS-LRR family. 14 singleton genes and 62 functional cis-elements were found. The structure of 27 proteins were constructed by homology modeling and divided into five different types. 34 differentially expressed genes of NBS-LRR genes were found in PM-resistant and PM-susceptible line. Expression of NBS-LRR genes were validated by qRT-PCR under PM stress and gene Lsi04g015960 with powdery mildew8 (RPW8)domain was significantly up-regulated in PM-resistant variety. Our study provides fundamental insights of NBS-LRR family genes in bottle gourd and find a potential candidate gene Lsi04g015960 for PM tolerance breeding.
650 1 4 _aBOTTLE GOURD
650 1 4 _aNBS-LRR FAMILY
650 1 4 _aPHYLOGENETIC ANALYSIS
650 1 4 _aPOWDERY MILDEW
650 1 4 _aEXPRESSION ANALYSIS
700 1 2 _aWang, J.
700 1 2 _aYang, C.
700 1 2 _aWu, X.
700 1 2 _aWang, Y.
700 1 2 _aWang, B.
700 1 2 _aWu, X.
700 1 2 _aLi, G.
856 4 0 _uhttps://drive.google.com/file/d/1Qza84hGz1tMg2ATYTDI_YLswWCe-cfRc/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942 _2Loc
_cREF1
008 250602s9999 xx |||||s2 |||| ||und|d
999 _c54712
_d54712