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245 1 0 _aThe antifungal metabolites isolated from maize endophytic fungus Fusarium sp. induced by OSMAC strategy
490 0 _vFitoterapia, 171, p.105710, 2023
520 3 _aSix new sesquiterpenes, fusarchlamols A-F (1, 2, 4-7); one new natural product of sesquiterpenoid, methyltricinonoate (3); and ten known compounds were found from Fusarium sp. cultured in two different media by the one strain many compounds strategy. The compounds (1, 2, and 4-11)were isolated from Fusarium sp. in PDB medium, and compounds (3-5, 8, and 10-17)were discovered from Fusarium sp. in coffee medium. Additionally, the configuration of 8 was first reported in the research by Mosher's method. The structures were established by 1D, 2D NMR, mass spectrometry, calculated ECD spectra, and Mosher's method. Compounds 1, 2, 6/7, 12, and 16 indicated significant antifungal activities against the phytopathogen Alternaria alternata isolated from Coffea arabica with MICs of 1 ?g/mL. The investigation on the anti-phytopathogen activity of metabolites can provide lead compounds for agrochemicals.
650 1 4 _aFUSARIUM SP.
650 1 4 _aSECONDARY METABOLITES
650 1 4 _aANTIFUNGAL ACTIVITY
650 1 4 _aOSMAC
700 1 2 _aSun, J.
700 1 2 _aYang, X. Q.
700 1 2 _aWan, J. L.
700 1 2 _aHan, H. L.
700 1 2 _aZhao, Y. D.
700 1 2 _aCai, L.
700 1 2 _aDing, Z. T.
856 4 0 _uhttps://drive.google.com/file/d/1LPKiQYhKOquhZnvecgZc208zssng054U/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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